ABSTRACT
The potential of an immunofluorescence test for detection of IgM antibodies against Schistosoma mansoni gut-associated antigens (IgM-IFT) was evaluated as a tool for studying aspects related to the schistosomiasis transmission in Ribeiräo Pires, in the metropolitan area of the capital of the State of Säo Paulo, Brazil. Children from a school with about 400 students, 6 to 18 years, were followed-up for two years. In the five surveys, carried out at 6-month intervals, from October 92 to October 94, serological (IgM-IFT) prevalence indices of 5.3 per cent, 5.8 per cent, 6.2 per cent, 2.9 per cent and 3.3 per cent were obtained. These indices were 7 to 10 times higher than the parasitological prevalence indices of 0.5 per cent, 0.5 per cent, 0.7 per cent, 0.4 per cent and 0 per cent determined by the Kato-Katz method. Seroconversion from IFT negative to positive was indicating possible newly acquired S. mansoni infection in three children. But confirmation of infection by fecal examination was possible in only one child. The IgM-IFT can constitute a valuable tool for the improvement of the vigilance program in low endemic areas for schistosomiasis, better characterizing the S. mansoni transmission in such areas.